Global Antihistamine Drugs Market Size, Share & Trends Analysis Report By Dosage Form (Oral Route, Parenteral, Other Dosage Forms), By Drug Class (H1 Antihistaminic, H2 Anti histaminic, H3 Anti histaminic, First Generation, Second Generation), By Type (OTC, Prescription-based), By Disease (Allergic Disorders, Stomach Disorders, Central Nervous System Disorders, Other Diseases), By Distribution Channels (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies) and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America), Global Economy Insights, Regional Outlook, Growth Potential, Price Trends, Competitive Market Share & Forecast (2024-2032)

The report offers the value (in USD Million) for the above segments.

Region: Global | Format: Word, PPT, Excel | Report Status: Published

 

Market Overview:

The Global Antihistamine Drugs Market size was valued at USD 281.15 million in 2023 and is projected to reach USD 626.95 million by 2032, with a CAGR of 9.32% during the forecast period of 2024 to 2032.

The market is growing because of things like more people getting allergies and gastrointestinal ailments and more people working on developing new dosage forms through research and development. Over the course of the forecast period, allergies and acid reflex are expected to continue to be the main drivers of market growth. For example, statistics released in April 2024 by the Asthma and Allergy Foundation of America indicates that each year, almost one-third of adult Americans and more than 25% of American children have eczema, food allergies, or seasonal allergies.

The prevalence of gastroesophageal reflux disease (GERD) was found to be 18.1% to 27.8% in North America, 8.8% to 25.9% in Europe, 2.5% to 7.8% in East Asia, 8.7% to 33.1% in the Middle East, 11.6% in Australia, and 23% in South America, according to a study published in Rawal Medical Journal in September 2022. As a result, it is projected that the high frequency of allergies and stomach issues will boost demand for antihistamines and propel market expansion.

In addition, it is projected that throughout the projection period, partnerships and cooperation among firms about the use of antihistamine drugs would support market expansion. For example, Astepro Allergy and Meghann Fahy collaborated in March 2023 to assist people with allergies. Astepro is a long-lasting nasal spray that can rapidly reduce allergy symptoms and begins to act in 30 minutes. As a result, these collaborations boost the use of antihistamines, which is expected to boost consumer acceptance and propel market expansion.

As a result, it is projected that the company's strategic initiatives and the growing prevalence of allergies and stomach problems will propel market expansion. However, the market's growth is being hindered by the branded products' patent expiration, the emergence of generic drugs, and the unfavorable side effects of antihistamine medications.

 
Market Drivers

Increasing Prevalence of Allergic Reactions Promotes the Demand for Antihistamine Drugs

  • The global rise in allergic reactions, including conditions like allergic rhinitis, conjunctivitis, urticaria, and anaphylaxis, is significantly driving the demand for antihistamine drugs. Factors such as increasing pollution levels, lifestyle changes, and greater exposure to allergens like dust, pollen, and animal dander have contributed to a growing number of allergy cases worldwide.
  • This rise in allergies has expanded the target population for antihistamines, both prescription and over-the-counter. Seasonal allergic rhinitis, commonly known as hay fever, impacts millions globally and boosts the consumption of antihistamine medications, as these drugs provide symptomatic relief by blocking histamine release. Furthermore, advancements in diagnostic tools have also led to better detection of allergies, which, in turn, propels the demand for effective antihistamine therapies. The trend toward self-medication in milder cases, along with growing awareness of allergy management, enhances the market’s growth potential.

Key Findings:

The strategic collaboration between Astepro Allergy and Meghann Fahy in March 2023 highlights the company's dedication to tackling the worldwide increase in allergy cases. Through this partnership, the fast-acting nasal spray Astepro which effectively reduces allergy symptoms will be more widely known and easier to obtain. With the help of Fahy's platform, the partnership aims to provide quick treatment for allergy sufferers and bolster the market for antihistamine medications.

Rising Investment in the Development of Advanced Technologies Increases the Innovation in Antihistamine Drugs

  • Investment in research and development for antihistamine drugs is surging as pharmaceutical companies look to innovate and improve the efficacy of these medications. With increasing competition and evolving patient needs, pharmaceutical companies are directing resources toward developing next-generation antihistamines that offer fewer side effects and prolonged action. Advancements in technology, such as targeted drug delivery systems and new molecular formulations, have enabled the creation of antihistamine drugs that reduce drowsiness, one of the most common side effects of first-generation antihistamines. These innovations are also leading to personalized medicine approaches, allowing patients to receive treatments better suited to their specific allergic responses. The increase in R&D investments also paves the way for more novel and combination drugs, further diversifying the market offerings.

Key Findings:

The market for addison's disease drugs is affected by technological improvements, as demonstrated by Antares Pharma's January 2022 release of favorable Phase I findings for ATRS-1902. The creation of ATRS-1902, which complies with the trend toward more accurate and practical treatment of the illness, is an innovation in targeted medication delivery systems for the treatment of acute adrenal insufficiency. The potential for better patient outcomes and a rise in the market's needs for specialized therapies is highlighted by this development.

 
Market Opportunities

Rise of Emerging Markets due to Expanding Consumer Base Enhancing the Reach of Antihistamine Medications

  • Emerging markets, particularly in regions like Asia-Pacific, Latin America, and the Middle East, offer immense opportunities for growth in the antihistamine drugs market. These regions are experiencing significant economic development and improvements in healthcare infrastructure, which are increasing the availability of pharmaceutical products, including antihistamines. Additionally, rising disposable incomes and growing awareness of allergies and their management are expanding the consumer base in these areas. Emerging markets are also witnessing an increase in urbanization and industrialization, contributing to higher pollution levels and allergen exposure, further driving demand for antihistamine medications. As healthcare access continues to improve in these regions, pharmaceutical companies have the opportunity to tap into these untapped markets by making antihistamine drugs more affordable and accessible to a larger population.

Rising Development of Biological Antihistamines Increases its Demand among the Consumers

  • Biological antihistamines, developed through biotechnology and often offering enhanced efficacy and targeted action, represent a growing segment within the broader antihistamine market. These advanced drugs have the potential to reduce allergic symptoms more effectively than traditional chemical-based antihistamines, particularly for patients who are unresponsive to conventional therapies. Biologics are also often associated with fewer side effects, which increases patient compliance and satisfaction. The development of biological antihistamines also aligns with the growing trend toward personalized medicine, where treatments are tailored to an individual’s unique biological profile. As biotechnological advancements continue, the market is seeing an increased interest from consumers seeking more effective and long-lasting treatments for allergies, providing a lucrative growth opportunity for pharmaceutical companies specializing in biologics.
 
Market Restraining Factors

Rising Side Effects of Antihistamine Drugs Reduces Patient Compliance

  • One of the major challenges faced by the antihistamine drugs market is the associated side effects, which can significantly reduce patient compliance. Traditional first-generation antihistamines, while effective, are known for causing drowsiness, dizziness, dry mouth, and other anticholinergic effects, which can impair daily functioning. These side effects often deter patients from long-term use, especially for those who require regular medication for chronic allergies. Even newer second-generation antihistamines, which are designed to be less sedating, can cause adverse effects like headaches, gastrointestinal disturbances, and cardiovascular risks in some cases. As patient awareness of these potential side effects grows, many are seeking alternative therapies, including non-pharmacological treatments or biologics, thus limiting the growth of the traditional antihistamine market.

Regulatory Challenges Limits the Product Availability

  • The antihistamine drugs market also faces regulatory challenges that can hinder product availability and market growth. Different countries have varying regulatory standards for drug approval, which can delay the introduction of new antihistamine drugs to the market. For instance, stringent regulations related to drug safety, efficacy testing, and post-marketing surveillance increase the time and cost of bringing new drugs to market. Moreover, the shift toward stricter labeling requirements for over-the-counter antihistamines, particularly those related to side effects and potential drug interactions, can further complicate market entry. These regulatory hurdles not only limit the ability of pharmaceutical companies to expand into new markets but also affect the profitability of new drug launches, making it a significant restraint for the global antihistamine drugs market.
 
Segmentation Analysis

The market scope is segmented because of by Dosage Form, by Drug Class, by Type, by Disease, by Distribution Channels.

By Dosage Form

Based on the Dosage Form of the market is segmented into Oral Route, Parenteral, Other Dosage Forms.

In the antihistamine drugs market, the oral route segment has traditionally dominated and continues to hold a significant share. The oral dosage forms, such as tablets, capsules, and liquids, are highly preferred by both patients and healthcare providers due to their convenience, ease of administration, and widespread availability. Oral antihistamines are often over-the-counter (OTC) medications, making them accessible for self-medication in cases of mild to moderate allergic reactions, such as allergic rhinitis or urticaria. Patients favor oral antihistamines because they can be taken without the need for healthcare professional supervision, making them highly practical for daily use or for managing seasonal allergies.

Moreover, oral antihistamines, especially second-generation drugs, are formulated to reduce sedative effects while providing long-lasting relief, making them more suitable for continuous use. This adds to their popularity, especially for chronic allergy sufferers. The lower cost of oral formulations compared to other dosage forms, such as parenteral (injectable) antihistamines, further strengthens their dominance in the market. The broad range of formulations, including chewable tablets, extended-release versions, and pediatric-specific liquids, enhances the versatility of oral antihistamines, catering to a diverse patient population. As a result, the oral route remains the most dominant segment in the antihistamine drugs market due to its accessibility, affordability, and ease of use.

By Drug Class

Based on the Drug Class of the market is segmented into H1 Anti-histaminic, H2 Anti-histaminic, H3 Anti-histaminic, First Generation, Second Generation.

In the Antihistamine Drugs Market, the Second Generation H1 Anti-histaminic segment dominated the market. This dominance is primarily due to the improved safety profile and reduced side effects of second-generation antihistamines compared to first-generation drugs. Unlike their predecessors, second-generation H1 antihistamines are less likely to cause drowsiness and sedation, a major drawback of first-generation antihistamines. This makes them more suitable for long-term use, particularly in patients with chronic allergies, such as allergic rhinitis and urticaria.

Second-generation antihistamines, including drugs like cetirizine, loratadine, and fexofenadine, have gained significant market share as they offer prolonged action with a lower risk of impairing cognitive and motor functions, allowing patients to maintain their daily activities without feeling sluggish. Furthermore, the growing awareness of allergy management and the increasing demand for over the counter (OTC) medications that do not impair daily functioning have contributed to the popularity of second-generation antihistamines.

Additionally, advancements in drug formulations, including extended-release options, have further driven the adoption of second-generation H1 antihistamines in both prescription and OTC markets. The segment's market dominance is expected to continue, driven by its superior patient compliance, safety, and widespread availability for treating a broad range of allergic conditions.

By Regional Snapshots

By region, Insights into the markets in North America, Europe, Asia-Pacific, Latin America and MEA are provided by the study. North America dominated the Antihistamine Drugs Market, driven by several key factors. The high prevalence of allergic conditions, such as allergic rhinitis, conjunctivitis, and urticaria, is a major driver in this region. The United States, in particular, has a significant population suffering from seasonal allergies, which boosts the demand for antihistamine medications. Additionally, North America benefits from well-established healthcare infrastructure and a large number of pharmaceutical companies engaged in developing and distributing advanced antihistamine drugs. High consumer awareness regarding allergy management and the easy availability of over-the-counter (OTC) antihistamines further strengthen the market in this region. Moreover, the growing trend of self-medication, with individuals purchasing OTC antihistamines, contributes to the market's dominance in North America.

In terms of future growth, the Asia-Pacific region is expected to be the fastest-growing market for antihistamine drugs. This is due to the rapidly increasing prevalence of allergies, urbanization, and industrialization, which are leading to higher exposure to allergens. Additionally, the region is witnessing improvements in healthcare infrastructure and increasing disposable incomes, which make antihistamine drugs more accessible to a larger population. The growing awareness of allergy diagnosis and treatment, along with the expansion of pharmaceutical companies into emerging markets like China, India, and Southeast Asia, is accelerating market growth. The increasing adoption of modern healthcare solutions and OTC antihistamines in these developing economies makes Asia-Pacific a lucrative region for future market expansion.

 
List of Companies Profiled
  • Sanofi
  • Boehringer Ingelheim International GmbH.
  • AstraZeneca
  • Johnson & Johnson Private Limited
  • Bayer AG
  • Merck & Co., Inc.
  • Prestige Consumer Healthcare Inc.
  • Hoffmann-La Roche Ltd.
  • Bristol-Myers Squibb Company
  • Almirall, S.A
  • Zenomed Healthcare Private Limited
  • Cadila Pharmaceuticals
  • Akorn Operation Company LLC
  • Pfizer Inc.
  • GlaxoSmithKline
  • Novartis AG
  • Mylan N.V.
  • Teva Pharmaceutical Industries Ltd.
 
Key Industry Developments

In January 2024, Dr. Reddy’s Laboratories (UK) Ltd launched its new allergy medication, Histallay (fexofenadine hydrochloride), in the UK general sales list (GSL) market.

In April 2023, Ocumension Therapeutics, an exclusive Chinese partner of Nicox SA, submitted a new drug application (NDA) for approval to commercialize Zerviate (cetirizine ophthalmic solution) 0.24% in China for ocular itching associated with allergic conjunctivitis. The product is expected to be launched in China in 2024.

 
Report Coverage

The report will cover the qualitative and quantitative data on the global Antihistamine Drugs Market. The qualitative data includes latest trends, market players analysis, market drivers, market opportunity, and many others. Also, the report quantitative data includes market size for every region, country, and segments according to your requirements. We can also provide customize report in every industry vertical.

 
Report Scope and Segmentations

Study Period

2024-32

Base Year

2023

Estimated Forecast Year

2024-32

Growth Rate

CAGR of 9.32% from 2024 to 2032

Segmentation

By Dosage Form, By Drug Class, By Type, By Disease, By Distribution Channels, By Region

Unit

USD Million

By Dosage Form

  • Oral Route
  • Parenteral
  • Other Dosage Forms

By Drug Class

  • H1 Anti-histaminic
  • H2 Anti-histaminic
  • H3 Anti-histaminic
  • First Generation
  • Second Generation

By Type

  • OTC
  • Prescription-based

By Disease

  • Allergic Disorders
  • Stomach Disorders
  • Central Nervous System Disorders
  • Other Diseases

By Distribution Channels

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

By Region

  • North America (U.S., Canada, Mexico)
  • Europe (Germany, France, UK, Italy, Spain, Russia, Rest of Europe)
  • Asia-Pacific (China, India, Japan, ASEAN, Rest of Asia-Pacific)
  • Latin America (Brazil, Mexico, Rest of Latin America)
  • MEA (Saudi Arabia, South Africa, UAE, Rest Of MEA)

 

Regional Analysis

North America accounted for the highest xx% market share in terms of revenue in the Antihistamine Drugs market and is expected to expand at a CAGR of xx% during the forecast period. This growth can be attributed to the growing adoption of Antihistamine Drugs. The market in APAC is expected to witness significant growth and is expected to register a CAGR of xx% over upcoming years, because of the presence of key Antihistamine Drugs companies in economies such as Japan and China.

The objective of the report is to present comprehensive analysis of Global Antihistamine Drugs Market including all the stakeholders of the industry. The past and current status of the industry with forecasted market size and trends are presented in the report with the analysis of complicated data in simple language.

Antihistamine Drugs Market Report is also available for below Regions and Country Please Ask for that

North America

  • U.S
  • Canada

Europe

  • Switzerland
  • Belgium
  • Germany
  • France
  • U.K
  • Italy
  • Spain
  • Sweden
  • Netherland
  • Turkey
  • Rest of Europe

Asia-Pacific

  • India
  • Australia
  • Philippines
  • Singapore
  • South Korea
  • Japan
  • China
  • Malaysia
  • Thailand
  • Indonesia
  • Rest Of APAC

Latin America

  • Mexico
  • Argentina
  • Peru
  • Colombia
  • Brazil
  • Rest of South America

Middle East and Africa

  • Saudi Arabia
  • UAE
  • Egypt
  • South Africa
  • Rest Of MEA
 
Points Covered in the Report
  • The points that are discussed within the report are the major market players that are involved in the market such as market players, raw material suppliers, equipment suppliers, end users, traders, distributors and etc.
  • The complete profile of the companies is mentioned. And the capacity, production, price, revenue, cost, gross, gross margin, sales volume, sales revenue, consumption, growth rate, import, export, supply, future strategies, and the technological developments that they are making are also included within the report. This report analysed 5 years data history and forecast.
  • The growth factors of the market are discussed in detail wherein the different end users of the market are explained in detail.
  • Data and information by market player, by region, by type, by application and etc., and custom research can be added according to specific requirements.
  • The report contains the SWOT analysis of the market. Finally, the report contains the conclusion part where the opinions of the industrial experts are included.
 
Key Questions
  • How much the global Antihistamine Drugs Market valued?
  • Which region has the largest share in 2024 for the global Antihistamine Drugs Market?
  • What are the driving factors for the market?
  • Which is the leading segment in the global market?
  • What are the major players in the market?
 
Research Scope of Antihistamine Drugs Market
  • Historic year: 2019-2023
  • Base year: 2024
  • Forecast: 2024 to 2032
  • Representation of Market revenue in USD Billion

Antihistamine Drugs Market Trends: Market key trends which include Increased Competition and Continuous Innovations Trends:

  • PUBLISHED ON : March, 2023
  • BASE YEAR : 2023
  • STUDY PERIOD : 2020-2032
  • COMPANIES COVERED : 20
  • COUNTRIES COVERED : 25
  • NO OF PAGES : 380

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