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The rapid rate that the research is progressing is caused by the increase in research funds as well as investments in making epigenetics development in science as well as a rise in the applications of epigenetics in drug discovery and drug development as well as the decreasing cost of genome sequencing which has lead to the huge growth of the market. It has been shown that epigentics has a great commercial application potential beyond cancer conditions and the market forecast for these areas increased significantly. Epigenetic mechanisms could participate directly or indirectly in the cancer, cardiovascular, reproductive, autoimmune disorders and different pathologies leading to cognitive functions deficiency.
These epigenetic pathways may be stimulated to certain extent due to external stimuli including the causative agents like heavy metals, pesticides, cigarette smoke, hormones, radiation etc. As a result, this may impact the function of these epigenetic pathways. The fact that epigenetics testing has already become a new approach in not only medical but also prenatal testing and also the rate of demand for such kits and assays is one of the major factors in future growth of the market. An upward health R&D spending trend all around the world is expected to provide this sector with a healthy growth over the projected period as well. For instance, according to the WHO report published in April 2023, the weighted average health GERD as% of GDP increased the most in high-income nations (0.25%) compared to the previous analysis (0.21%).
This can be attributed to the rise of GERD in several of these high-income nations, with the Republic of Korea reporting the biggest rise (from USD 3.8 billion to USD 4.5 billion in 2020), followed by Greece (from USD 513 million to USD 598 million in 2020). Over 15% was reported as an upsurge in both nations. In addition, for instance, in February 2021, the International Cancer Genome Consortium (ICGC) launched the ICGC ARGO Data Platform, a significant step forward after the ICGC 25K Data Portal. ARGO is a global initiative to promote cancer genetics by providing superior-quality clinical, genomic, and molecular data to worldwide researchers.
The report will cover the qualitative and quantitative data on the global Epigenetics Market. The qualitative data includes latest trends, market players analysis, market drivers, market opportunity, and many others. Also, the report quantitative data includes market size for every region, country, and segments according to your requirements. We can also provide customize report in every industry vertical.
By Product & Service (Kits & Reagents, Enzymes, Instruments and Accessories, Software, Service), By Methods (DNA Methylation, Histone Modifications, Other Methods), By Technique (NGS, PCR & qPCR, Mass Spectrometry, Sonication, Other Techniques), By Application (Oncology, Metabolic Diseases, Immunology, Developmental Biology, Cardiovascular Diseases, Other Applications), By End User (Academic & Research Institutes, Pharmaceutical & Biotechnology Companies, Hospitals & Clinics).
Study Period | 2024-32 |
Base Year | 2023 |
Estimated Forecast Year | 2024-32 |
Growth Rate | CAGR of 18.8% from 2024 to 2032 |
Segmentation | By Product & Service, By Methods, By Technique, By Application, By End User, By Region |
Unit | USD Billion |
By Product & Service |
Antibodies ChiP-seq Kits Bisulfite Conversion Kits Whole Genome Amplification Kits 5-hmC and 5-mC Analysis Kits Histones Other Kits & Reagents
DNA-modifying Enzymes Protein-modifying Enzymes Other Enzymes
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By Methods |
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By Technique |
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By Application |
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By End User |
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By Region |
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In August 2023, PacBio (US) acquired Apton Biosystems (US) to accelerate the development of a next-generation, high-throughput, short-read sequencer.
In March 2022, Thermofisher Scientific Inc (US) launched the CE IVD Marked Next Generation Sequencing Instrument designed to be used in in clinical laboratories to perform both diagnostic testing and clinical research on a single instrument.
In January 2022, Illumina, Inc. (US) entered into an agreement with SomaLogic (US) to introduce SomaScan Proteomics Assay in high throughput next-generation sequencing (NGS) platforms manufactured by Illumina.
By Product & Service
By Technique
By Methods
By Application
By End User
By Region
The report also helps in understanding Global Epigenetics Market dynamics, structure by analyzing the market segments, and project the Global Epigenetics Market size. Clear representation of competitive analysis of key players by type, price, financial position, product portfolio, growth strategies, and regional presence in the Global Epigenetics Market make the report investor’s guide.
The market scope is segmented because of by Product & Service, by Methods, by Technique, by Application, by End User.
By Product & Service
Based on the Product & Service of the market is segmented into Kits & Reagents (Antibodies, ChiP-seq Kits, Bisulfite Conversion Kits, Whole Genome Amplification Kits, 5-hmC and 5-mC Analysis Kits, Histones, Other Kits & Reagents), Enzymes (DNA-modifying Enzymes, Protein-modifying Enzymes, Other Enzymes), Instruments and Accessories, Software, Service.
As the market is segmented on the basis of products, it covers reagents, kits, instruments and enzymes etc. and services. The reagents category represented 31.50% part of the overall revenue in 2022 and was the leading segment. A big pie of this category can be accredited to the high level of reagents consumption required in lab-based investigations. The scientific research of epigenetics works mainly with two types of reagents - histones and DNA modifiers. One of the main discoveries in genetics is 'epigenetics', this represents the idea of inherited, maybe reversible changes, in gene expression, that occurs but don't change the DNA sequence; however, this information transfers to the next generation. Changing the switch might cause the genes to be turned on or turned down, but without the DNA, the process all about how they work.
DNA methylation, RNA regulation, and histone modification are the ones that were the ingredients for comprehensive experiments. Components as such are necessary for gene controlling. From the other side, however, kits segment is theoretically prophesied to record the highest CAGR of approximately 15.4% over the same period. Therefore, the rescue kit demand is dependent on trends, such as an increase in the numbers of chronic illnesses, a growing aging population and an increase in the use of treatment approaches based on epigenetics. Alongside this, greater understanding, that combined with the increasing companies conducting development on those hi-tech kits, will contribute to the increasing popularity of these market sectors.
By Methods
Based on the Methods of the market is segmented into DNA Methylation, Histone Modifications, Other Methods (non-coding RNA and chromatin remodeling).
By methods, the line is categorized into major epigenetic mechanisms including DNA methylation, histone methylation, histone acetylation, major noncoding RNA, microRNA modification and chromatin structures. The pharmaceutical segment had the largest of 69.23% revenue in 2022 amongst all other segments. DNA marked chemically and enzymatically for epigenetic processes like DNA methylation wherein methylation of DNA is used as a method to determine the methylated DNA. The DNA methylation method will assist to unwind the complicated health processes associated with development of diseases that are disease-specific, and in the same way, design individualized drug therapies for patients depending on their individual need and as well as the treatment outcome. With demand for DNA methylation methods continuing to surge, the markets are anticipating growth. With the growing technology, we tend to see more and more genotypes-specific DNA methylation in a global scale being assessed on a regular basis.
The histone acetylation segment is going to retain the highest compound annual growth rate of 15.8% over the forecast period (2024-2032) thanks to the rise of the innovative techniques that help to enhance its efficiency. Extensive series of the investigations have shown that histone acetylation can recommend as target of therapy in diseases, like, solid tumors, inflammation, leukemia, etc. Among the HAT subfamilies that have been studied so far, those that stand out the most include NFA15, PCAF, GNC5, HTA1, HBO1, and MORC4. DNA methylation is a huge contributor to the cancer process which is mainly considered as an activity of HAT1. The broad scope in the therapeutic areas can create a blockbuster market, thus, the demand will increase in the period under study.
By Technique
Based on the Technique of the market is segmented into NGS, PCR & qPCR, Mass Spectrometry, Sonication, Other Techniques (magnetic separators and microarrays).
This means that the effective method for reading, analysing, and identifying epigenetic changes in DNA sequences is Next-Generation Sequencing (NGS). Another two techniques that are very significant in the epigenetics are luminescence (qPCR) and luminescence (qPCR), which help to get multiple copies of a specific section of DNA, including the parts that are being regulated by epigenetic mechanisms. A technology used in more epigenetics research is mass spectrometry, which measures the amount and presence of chemicals and proteins that form the building blocks of epigenetic processes. During its research, methods for breaking down cellular structures such as sonication are also used compare to DNA, RNA and proteins. Such approaches, together with additional methods like Chromatin immunoprecipitation (ChIP) and Bisulfite sequencing, form an important part of a general epigenome investigation and the consequent implications for health and diseases.
By Application
Based on the Application of the market is segmented into Oncology, Metabolic Diseases, Immunology, Developmental Biology, Cardiovascular Diseases, Other Applications (neurology, infectious diseases, and gynecology).
The world chapter, in turn, is based on applications and is further subdivided into an oncology segment, a metabolic diseases segment, an immunology segment, a developmental biology segment, a cardiovascular diseases segment, other applications. The oncology segment of this application generated the most sales, capturing a share of as much as 69.23% in 2023. Presently, cancer is the most investigated subject using these epigenetic methods. with cancer cases see a noticeable upswing, is most likely will there be an expansion on the market for pharmacogenetic diagnostics of cancer. With figures released by the American Cancer Society, it is projected that thirty-one hundred people will be diagnosed with cancer in 2022, with cancer epidemics resulting in about six hundred thousand deaths.
However, with the highest estimated CAGR of 15.7% among all the sub-end markets of the cancer market, the non-oncology application segment is forecast to be the fastest growing segment. The attention onto epigenetics studies were constantly increased by non-oncology disease indication. Consequent to investigated applications of epigenetics, doctors realize the opportunities to treat broad range of conditions, including neurological disorders, such as Alzheimer’s, Parkinson’s and others, as well as developmental disorders, such as ASD’s, CVD’s, metabolic disorders, and many others. The application of epigenetics not just in oncology but also in non-oncology indications would be high in the near future, which will positively reflect on the development of this section.
By End User
Based on the End User of the market is segmented into Academic & Research Institutes, Pharmaceutical & Biotechnology Companies, Hospitals & Clinics.
On the basis of end user, the pharmaceutical & biotechnology companies segment held the largest epigenetics market size in 2023 and is expected to remain dominant during the forecast period, due to R & D for drug resistance developed by microorganisms, oncology, molecular aspects of cancer, and drug discovery for non-oncology applications.
The epigenetics market has got divided into those five major parts with the names serving as North America, Europe, Asia Pacific, Latin America, Middle East and Africa. In the year 2023, North America takes the lead in the market share of epigenetics while the forecast shows the trend to maintain its position during the expected period. Presence of epigenetics production units and NGS-related initiations by government and private sectors for its development and adoption are some of the major characteristics of the market's growth.
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15 Apr 2024