Protein Expression Market Size, Share & Trends Analysis Report By Expression system (Bacterial, Yeast, Insect, Mammalian, Cell-free systems), By Application (Therapeutic proteins, Research applications, Industrial enzymes, Biologics production), By End User (Biotechnology and pharmaceutical companies, Academic and research institutions, Contract research organizations (CROs), Others), Covid-19 Impacts, Global Economy Insights, Regional Outlook, Growth Potential, Price Trends, Competitive Market Share & Forecast, 2023 - 2031

Region: Global | Format: Word, PPT, Excel | Report Status: Published

Market Overview:

Global Protein Expression Market size was USD 3.27 Billion in 2022. Covid-19 impacts have been unprecedented and staggering on a global scale. With the pandemic leading to positive demand shocks for the Protein expression market across all domains and region between 2023 and 2031. The market is projected to grow at a CAGR of 11.4% from USD 2.94 billion in 2021 to USD 9.32 Billion in 2031 according to a new report by Intellectual Market Insights Research. The Sudden rise in CAGR is attributed to this market growth returning to the pre-pandemic level once the pandemic is over.

The global protein expression market refers to the market for products and services used to study, analyze, and produce proteins. Protein expression is the process of making proteins from genetic information stored in DNA, and it is a useful instrument in many areas, including nanotechnology, medicines, and research. Expression vectors, competent cells, reagents, tools, and services for protein expression research and manufacturing are among the goods and services available in the market.

The worldwide protein expression market encompasses a wide range of protein expression methods and applications, including mammalian expression, bacterial expression, yeast expression, insect expression, and cell-free expression. Academic research institutes, pharmaceutical and biotechnology firms, and contract research groups are among the end-users served by the industry. (CROs).

The market for Protein expression has grown significantly in recent years, with many popular titles and series achieving global success and attracting a diverse audience.

The Protein Expression market research report comprises a thorough examination of the current and future scenario of this industry vertical. The research highlights major trends and opportunities, as well as challenges, for various segments and sub-segments, while broadening the company horizon. The study report also includes extensive information based on past and present patterns across several industry verticals to help find various expansion prospects. Throughout the forecast period, several estimations regarding market share, market size, and industry growth rate are presented. The research includes information on competitive analysis as well as consumption habits and pricing strategies depending on the Protein Expression market.

Scope of Protein Expression Market Report:

A recent market research report added to repository of Intellectual Market Insights Research is an in-depth analysis of Global Protein Expression Market. On the basis of historic growth analysis and current scenario of Protein Expression market place, the report intends to offer actionable insights on global market growth projections. Authenticated data presented in report is based on findings of extensive primary and secondary research. Insights drawn from data serve as excellent tools that facilitate deeper understanding of multiple aspects of global Protein Expression market. This further helps users with their developmental strategy.

This report examines all the key factors influencing growth of global Protein Expression market, including demand-supply scenario, pricing structure, profit margins, production and value chain analysis. Regional assessment of global Protein Expression market unlocks a plethora of untapped opportunities in regional and domestic market places. Detailed company profiling enables users to evaluate company shares analysis, emerging product lines, pricing strategies, innovation possibilities and much more.

The report covers the all the aspects of industry with dedicated study of key players that includes market leaders, followers and new entrants by region. PORTER, SVOR, PESTEL analysis with the potential impact of micro-economic factors by region on the market have been presented in the report. External as well as internal factors that are supposed to affect the business positively or negatively have been analyzed, which will give clear futuristic view of the industry to the decision makers.

Protein Expression Market Drivers:

There are several drivers that are contributing to the growth of the Protein expression market, including:

The industry is expanding as Growing demand for biopharmaceuticals.

Biopharmaceuticals, or therapeutic medicines created through biological processes, are increasingly being used to treat a variety of illnesses. Protein expression is a crucial stage in the production of these drugs, and as the demand for biopharmaceuticals grows, so will the demand for protein expression goods and services.

Increasing demand for Technological advancements in protein expression techniques

Protein expression techniques have advanced technologically, resulting in the creation of more efficient and cost-effective ways of making proteins. High-throughput screening techniques, genome editing tools, and better expression vectors and cell lines are among these technologies. The market for protein expression goods and services is anticipated to grow as these techniques develop.

Protein Expression Market Trends:

Increasing adoption of single-use technologies expanding use supports the market trend.

In the protein expression industry, single-use technologies such as disposable bioreactors, filtration devices, and chromatography columns are getting traction. These technologies have several benefits over conventional stainless-steel equipment, such as lower prices, quicker startup times, and lower contamination risks. Consequently, many biopharmaceutical firms and contract manufacturing organizations (CMOs) are incorporating single-use technologies into their protein expression methods.

The market trend is supported by the Growing emphasis on precision medicine

In the healthcare sector, precision medicine is a new movement that entails customizing medical care for each patient based on their genetic composition. In order to create proteins that are unique to a patient's genetic makeup, protein expression is a crucial stage in the creation of tailored treatments. The demand for protein translation goods and services that can support customized treatments is anticipated to rise as precision medicine continues to make ground.

Protein Expression Market Restraining Factors:

The growth of the industry is hampered by High expense of protein expression systems

The price of protein expression systems is a significant barrier to the growth of the global protein expression industry. The total expense of protein expression may rise as a result of the costly hardware and chemicals needed for protein expression systems. Due to the expensive cost of protein expression systems, it is challenging for small and medium-sized businesses (SMEs) to engage in protein expression technologies, which restricts the market's expansion.

Market expansion is constrained by a Professional shortage

Another significant market restraint is the shortage of experts in the area of protein translation. There is a dearth of competent experts with the necessary knowledge and experience for the process of protein expression. The creation and marketing of protein-based medicines and products may be delayed as a result of the trained labor scarcity, which may have a detrimental effect on the market's expansion.

Report Coverage:

The report will cover the qualitative and quantitative data on the global protein expression market. The qualitative data includes latest trends, market players analysis, market drivers, market opportunity, and many others. Also, the report quantitative data includes market size for every region, country and segments according to your requirements. We can also provide customize report in every industry vertical.

Report Scope and Segmentations:

Study Period


Base Year


Estimated Forecast Year


Growth Rate

CAGR of 11.4% From 2023 To 2031


Expression system, Application and Regions.


USD Billion

Expression system

·         Bacterial

·         Yeast

·         Insect

·         Mammalian

·         Cell-free systems


·         Therapeutic proteins

·         Research applications

·         Industrial enzymes

·         Biologics production

End User

·         Biotechnology and pharmaceutical companies

·         Academic and research institutions

·         Contract research organizations (CROs)

·         Others

By Region

·         North America (U.S., Canada, Mexico)

·         Europe (Germany, France, UK, Italy, Spain, Russia, Rest Of Europe)

·         Asia-Pacific (China, India, Japan, ASEAN, Rest of Asia-Pacific)

·         Rest of the world

The Key Player Strategies in the Market:

  • In February 2021, Thermo Fisher Scientific announced a partnership with CSL Limited to develop and commercialize monoclonal antibody (mAb) and recombinant protein-based therapies.
  • In April 2021, Merck KGaA launched a new Protein A resin for large-scale purification of monoclonal antibodies.
  • In July 2021, Danaher Corporation completed the acquisition of Aldevron, a provider of plasmid DNA, mRNA, and proteins for use in cell and gene therapies.
  • In March 2021, GenScript Biotech Corporation announced a $300 million investment in a new biomanufacturing facility in Nanjing, China, to expand its capabilities in protein expression and cell therapy.

Protein Expression Market Players Analysis:

Here is a list of some of the companies profiled in the Protein Expression Market:

  • Thermo Fisher Scientific Inc.
  • Merck KGaA
  • Agilent Technologies, Inc.
  • Bio-Rad Laboratories, Inc.
  • GenScript Biotech Corporation
  • Lonza Group Ltd.
  • Promega Corporation
  • Takara Bio Inc.
  • Sigma-Aldrich Corporation (part of Merck KGaA)

Protein Expression Market Players & Competitor Analysis: The report covers the key players of the industry including Company Profile, Product Specifications, Production Capacity/Sales, Revenue, Price and Gross Margin 2022-2031 & Sales with a thorough analysis of the market’s competitive landscape and detailed information on vendors and comprehensive details of factors that will challenge the growth of major market vendors.

Protein Expression Market Segmentation Analysis:

The global protein expression market can be segmented by expression system, application, end user, and region.

By Expression system: This segmentation criterion categorizes the market based on the type of expression system used for protein expression. Common types of expression systems include bacterial, yeast, insect, mammalian, and cell-free systems.

By Application: This criterion divides the market based on the intended use of the expressed proteins. The protein expression market can be segmented based on applications such as therapeutic proteins, research applications, industrial enzymes, and biologics production.

By End-user: This segmentation criterion categorizes the market based on the end-users of protein expression products. End-users can include biotechnology and pharmaceutical companies, academic and research institutions, contract research organizations (CROs), and others.

By Region: This criterion divides the market based on geographical regions. The global protein expression market can be segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa.

The report also helps in understanding Global Protein Expression Market dynamics, structure by analyzing the market segments, and project the Global Protein Expression Market size. Clear representation of competitive analysis of key players by type, price, financial position, product portfolio, growth strategies, and regional presence in the Global Protein Expression Market make the report investor’s guide.

Global Protein Expression Market Regional Analysis:

North America accounted for the highest xx% market share in terms of revenue in the Protein Expression market and is expected to expand at a CAGR of xx% during the forecast period. This growth can be attributed to the growing adoption of Protein Expression. The market in APAC is expected to witness significant growth and is expected to register a CAGR of xx% over upcoming years, because of the presence of key Protein Expression companies in economies such as Japan and China.

The objective of the report is to present comprehensive analysis of Global Protein Expression Market including all the stakeholders of the industry. The past and current status of the industry with forecasted market size and trends are presented in the report with the analysis of complicated data in simple language.

Regional Snapshots:

The global protein expression market is expected to experienced growth in all regions, including North America, Europe, Asia Pacific, Latin America and Middle east and Africa. Here is some information on the market in each of these regions.

North America: The North American protein expression market is driven by the presence of several biotechnology and pharmaceutical companies, and a strong focus on R&D. The US is the largest market in this region due to the presence of major market players and increasing investments in biotechnology research.

Europe: The European protein expression market is driven by increasing investments in R&D activities, growing demand for biologics, and a well-established healthcare infrastructure. The UK, Germany, and France are the major markets in this region due to their large base of biotechnology and pharmaceutical companies.

Asia Pacific: The Asia Pacific protein expression market is driven by increasing investments in biotechnology research and development, rising demand for biologics, and growing healthcare expenditure. China, Japan, and India are the major markets in this region due to their large population base, rising healthcare infrastructure, and growing biotechnology industry.

Latin America: The Latin American protein expression market is driven by increasing government initiatives to promote biotechnology research and development, growing healthcare infrastructure, and rising demand for biologics. Brazil, Mexico, and Argentina are the major markets in this region due to their large population base and growing biotechnology industry.

Middle East and Africa: The Middle East and Africa protein expression market is driven by increasing investments in biotechnology research and development, growing healthcare infrastructure, and rising demand for biologics. The major markets in this region include Saudi Arabia, South Africa, and United Arab Emirates.

Protein Expression Market Report is also available for below Regions and Country Please Ask for that

North America
  • U.S
  • Canada
  • Switzerland
  • Belgium
  • Germany
  • France
  • U.K
  • Italy
  • Spain
  • Sweden
  • Netherland
  • Turkey
  • Rest of Europe
  • India
  • Australia
  • Philippines
  • Singapore
  • South Korea
  • Japan
  • China
  • Malaysia
  • Thailand
  • Indonesia
  • Rest Of APAC
Latin America
  • Mexico
  • Argentina
  • Peru
  • Colombia
  • Brazil
  • Rest of South America
Middle East and Africa
  • Saudi Arabia
  • UAE
  • Egypt
  • South Africa
  • Rest Of MEA

Points Covered in the Report:

The points that are discussed within the report are the major market players that are involved in the market such as market players, raw material suppliers, equipment suppliers, end users, traders, distributors and etc.

The complete profile of the companies is mentioned. And the capacity, production, price, revenue, cost, gross, gross margin, sales volume, sales revenue, consumption, growth rate, import, export, supply, future strategies, and the technological developments that they are making are also included within the report. This report analysed 5 years data history and forecast.

The growth factors of the market are discussed in detail wherein the different end users of the market are explained in detail.

Data and information by market player, by region, by type, by application and etc., and custom research can be added according to specific requirements.

The report contains the SWOT analysis of the market. Finally, the report contains the conclusion part where the opinions of the industrial experts are included.

Key Industry Developments:

  • In January 2021, Bio-Techne Corporation acquired Asuragen, Inc., a molecular diagnostics company, to expand its product portfolio and capabilities in the diagnostics market.
  • In February 2021, Thermo Fisher Scientific and CSL Limited announced a partnership to develop and commercialize monoclonal antibody (mAb) and recombinant protein-based therapies.
  • In March 2021, GenScript Biotech Corporation announced a $300 million investment in a new biomanufacturing facility in Nanjing, China, to expand its capabilities in protein expression and cell therapy.
  • In April 2021, Merck KGaA launched a new Protein A resin for large-scale purification of monoclonal antibodies.
  • In June 2021, Bio-Rad Laboratories, Inc. announced the launch of a new protein expression platform, the Experion™ Pro260 system, for the high-throughput production of recombinant proteins.
  • In July 2021, Danaher Corporation completed the acquisition of Aldevron, a provider of plasmid DNA, mRNA, and proteins for use in cell and gene therapies.
  • In August 2021, Takara Bio Inc. announced the launch of a new high-yield protein expression system, the Takara Bio Protein Expression System, for the efficient production of recombinant proteins.

Key Questions:

  • How much the global Protein Expression Market valued?
  • Which region has the largest share in 2021 for the global Protein Expression Market?
  • What are the driving factors for the market?
  • Which is the leading segment in the global market?
  • What are the major players in the market?

Research Scope of Protein Expression Market:

  • Historic year: 2018- 2021
  • Base year: 2022
  • Forecast: 2023 to 2031
  • Representation of Market revenue in USD Million

Protein Expression Market Trends: Market key trends which include Increased Competition and Continuous Innovations Trends:

Frequently Asked Questions

  • How Much the Global Protein expression Market Valued?

    During the forecast period, the global Protein expression market is expected to grow at a compound annual growth rate (CAGR) of 11.4 %, and it is projected to reach a market size of USD 9.32 billion by 2031. as of 2022, the market was valued at USD 3.27 billion.

  • Which Region has the Largest Share in 2022 for the Global Protein Expression Market?

    North America has the largest share for the global Protein expression market. This is due to factors such as presence of a large number of pharmaceutical and biotech companies in the region, increasing research activities in the field of proteomics, and growing demand for personalized medicine.

  • What are the Driving Factors for the Market?

    The driving factors for the global Protein expression market Increasing investment in biotechnology research, Rise in contract research outsourcing, Advancements in proteomics research are the driving factors for the market

  • What are the Major Players In The Market?

    Thermo Fisher Scientific Inc., Merck KGaA, Agilent Technologies, Inc., Qiagen N.V., Promega Corporation, Takara Bio Inc.and others are the major players in the market.

  • PUBLISHED ON : March, 2023
  • BASE YEAR : 2022
  • STUDY PERIOD : 2020-2032
  • NO OF PAGES : 194

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